XIONG Zhaohui1; WU Wenrong1; HUANG Xuanjie1*;WU Wenrong 1; NI Xiaomin 1
1 The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong Province, China, 518000.
* HUANG Xuanjie is the corresponding author. https://orcid.org/0000-0002-8811-7937
Article History Received 14 June 2021 Accepted 25 July 2021 Published 30 September 2021
Cite this Article XIONG Zhaohui; WU Wenrong; HUANG Xuanjie;WU Wenrong; NI Xiaomin. Fasting Has Limited Impacts on the Result of Penicillin Allergy Skin Test: An Observation Study [J].Medical Research, 2021.3(3):9-14, http://dx.doi.org/mrhk/10.6913/MRHK.202109_3(3).0002
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Objective Penicillin allergy skin test is a common procedure in nursing care. Many patients can only do an allergy skin test on fasting due to the disease condition. However, whether or not the fasting state has any effects on the skin testing results remains unclear. Therefore, this study aimed to determine the effects of fasting on the results of penicillin allergy skin tests.
Methods This observational cohort study analyzed the clinical data of 200 patients undergoing a penicillin skin test in the emergency center of The Seventh Affiliated Hospital of Sun Yat-sen University from August 1, 2020, to December 31, 2020, of which 100 cases were fasting patients and 100 were non-fasting patients. The information including gender, age, allergy, skin test results, dizziness, and gastrointestinal symptoms were collected and compared.
Result Among the 200 patients, five patients (2.5%) tested positive for the penicillin-allergy skin tests. Three patients (3%) tested positive in the fasting group, while two patients (2%) in the non-fasting group tested positive (Relative Risk: 1.5; 95% Confidence Interval: 0.3055 to 7.397; P=0.65).
Conclusion These data suggest that fasting may have limited impacts on the results of penicillin allergy skin tests.
Keywords Fasting; Penicillin skin test; Results; Observation analysis